Super-enhancers in cancer cells trigger DNA breaks and error-prone repair cycles

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

Tiny molecules called tRNA halves may contribute to prostate cancer cell growth

Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new ...

Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
News-Medical.Net on MSN

Study identifies a powerful strategy to overcome drug resistance in breast cancer

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Communications , identifies a powerful strategy to overcome drug resistance in ...
University of California

New vulnerability identified in aggressive breast cancer

By targeting proteins used to splice genes, UC San Diego researchers have unlocked a new approach to treating triple-negative ...
Xinhuanet

Study finds cancer cells harm own DNA during growth, pointing to potential path for therapy

JERUSALEM, Jan. 21 (Xinhua) -- Israeli researchers have found that cancer cells can damage their own DNA through the same process that drives their aggressive growth, revealing a key vulnerability ...
EurekAlert!

Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...